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2.3.1 The System Xc-GSH-GPX4 axis The heat shock protein 90 (HSP90) plays an important role in protein maturation, stabilisation, and activation (Wickramaratne et al., 2023)
Human pharmacokinetics, doseresponse, and mechanism validation remain limited
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The pH during the reaction is low, which may cause chromogenic inhibition
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IV glutathione often provides immediate benefits within hours for a few days
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