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The MGF E-peptide has been shown to significantly increase the proliferative lifespan and delay senescence of satellite cells isolated from neonatal and young adult human muscle, while having attenuated effects in cells from older adults establishing an age-dependent satellite cell responsiveness to MGF that underpins its utility as a sarcopenia and muscle ageing research tool
The metabolites showed much lower toxicity compared to the parent compounds [423]
10.3390/antiox13080922 68 ZhangM.MaB.YangS.WangJ.ChenJ
They are formulated for intravenous, oral and intranasal administration
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