Chen, T., Song, J., Liu, H., Zheng, H
TMAO has been implicated in chronic low-grade inflammation and altered glucose metabolism in diabetes, although causality remains under investigation
We also used a self-controlled case series design [19], which comprised of new users of GLP-1 RAs ( n = 85,717 ) or SGLT-2 inhibitors ( n = 78,366 ) or DPP-4 inhibitors ( n = 35,762) from 2014 to 2022
Tirzepatide for MASH with fibrosis 15 mg produced a large majority disease-resolution rate versus a small placebo rate: Loomba NEJM 2024 (SYNERGY-NASH)
Their mechanism of action makes them unique due to their potential for weight loss, low risk of hypoglycemia, and A1C-lowering potential with effects on both fasting and postprandial blood glucose values