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Altered intestinal permeability (leaky gut) allows the passage of food antigens, toxins, bacteria, and microbial products, promoting inflammation and dysregulated immune responses, triggering autoimmunity through various mechanisms [188]

It plays a large role in metabolic and hormonal functions, creating digestive enzymes and delivering nutrients to our cells

The researchers documented severe T-cell hyperproliferation and pronounced mitochondrial lipid oxidative damage, concluding that oxidative stress is a shared mechanistic basis for the debilitating fatigue seen in both conditions

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SGLT2 inhibitors as calorie restriction mimetics: insights on longevity pathways and age-related diseases

The product will be marketed and commercialized in Canada by Apotex Inc., the applicant of record and Canada's largest pharmaceutical company