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[97] These strict measures have been opposed by some of the leading kava scientists
The observed inconsistencies between available in planta, in vitro and in vivo (cell factory) data, however, led us to hypothesize that arGSTs might not (only) have the literature-proposed transport function but could play a central role in the biosynthetic step from leucoanthocyanidins ( 2 ) to anthocyanidins ( 3 )
However, following therapeutic doses, a healthy liver is able to detoxify NAPQI rapidly due to the presence of reduced glutathione (GSH)
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