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A 2026 follow-up study showed a similar boost for tirzepatide, where women pairing the drug with HRT achieved a 19% weight reduction compared to 14% for those taking the medication alone

This information is general guidance, not medical advice

Thats why we pair GLP-1s with strength training, lifestyle tools, and ongoing support at Josie to help you build habits that last, even after stopping

Tips to manage side effects Eat smaller meals and avoid very fatty or spicy foods to help reduce nausea

These symptoms may also present in an ulcerated acral lentiginous melanoma, which could appear on areas like the top of a toe