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If you have a history of B12 deficiency, malabsorption issues, or are vegetarian/vegan with marginal B12 status, the weekly B12 injection provides protection during the high-risk period of rapid weight loss

If you miss a dose by more than 4 days, the manufacturer recommends skipping that dose and resuming on your next scheduled day

Testing serum levels of B12 can be done, but serum B12 levels tend to be highly inaccurate

There may also be minor irritation at the injection site, for example, redness, tenderness, or a brief burning sensation where the NAD+ solution is injected subcutaneously

Vegetarians and Vegans Since vitamin B12 is mainly found in animal products, vegetarians and vegans are at a higher risk of deficiency

These conditions are associated with an increased risk of thyroid carcinoma and MEN 2 syndrome when using GLP-1 medications