Until recently, semaglutide treatments were mostly available as injections
~ AlphaMD Scroll through fitness social media for five minutes and you'll see plenty of guys casually discussing their "TRT" protocol, yet the doses they mention would make an endocrinologist do a double take
Therefore, the SHAPE study (Real-World Weight Loss Observed With S emaglutide and Tirzepatide in Patients with Overweig H t or Obesity A nd Without Ty PE 2 Diabetes) aimed to evaluate the effectiveness of semaglutide 2.4 mg and tirzepatide in patients with overweight or obesity and without T2DM in routine clinical practice over a 1-year follow-up period
"This work not only highlights the potential off-target effect of semaglutide as an effective drug to treat metabolic osteoarthritis," the team from China and the US writes in their published paper, "but also reveals a weight loss-independent repair mechanism." In addition to mouse experiments, the researchers also conducted a randomized human trial to assess the effects of semaglutide on pain, mobility, and tissue degradation in individuals with osteoarthritis and obesity
Beta-catenin signaling in hepatic development and progenitors: Which way does the WNT blow
Ozempic is an FDA-approved medication for two things