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L-carnitine is primarily synthesized in the liver and transported via the bloodstream to cardiac and skeletal muscle, which rely on L-carnitine for fatty acid oxidation yet cannot synthesize it (8)

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Under physiological conditions, cellular permeability to Na+ and K+ ions forms the basis for electrophysiological stability

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In conclusion, supplementation with 200 g/d L-carnitine fumarate significantly reduces hepatic triglyceride concentration, even when NEFA and hepatic triglycerides are low