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While gastrointestinal side effects were common, they were largely mild to moderate and aligned with expectations for GLP-1based therapies

A medically guided plan can help identify which barriers may be slowing progress and what adjustments may help

NINA MOINI: Oh, are you there, doctor

Diarrhoea may irritate haemorrhoids, while constipation can cause straining that leads to anal fissures

Methods A comprehensive literature search was conducted to synthesize the current preclinical and clinical evidence

For many people, food is a reliable source of small dopamine hits. Taking that away abruptly can blunt reward processing, leaving patients feeling emotionally flat