& Orskov, C
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The side effects that do exist are narrow and well-characterized: gastrointestinal upset at higher oral doses, a distinctive fishy body odor from a carnitine metabolite, and one genuinely debated caveat an indirect cardiovascular signal involving the gut-derived metabolite TMAO
AOD-9604 is a downstream fragment of GH with isolated lipolytic activity that doesn't engage GH receptors
Overall, we think this is an acceptable profile & orfo[rglipron] 36 mg generally looks in line vs Wegovy 2.4 mg/oral sema[glutide] 50 mg, Akash Tewari, global head of biopharmaceutical research with Jefferies, wrote in a research note
Blood Sugar Control: They stimulate the pancreas to release insulin when blood sugar is high and block the release of glucagon, thereby stabilizing glucose levels