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GCGR signaling in hepatocytes activates adenylyl cyclase, increasing cAMP and driving glycogenolysis, gluconeogenesis, and critically, hepatic fatty acid oxidation via CPT1a upregulation
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To minimize the risk of overdose, do not take more medication than your healthcare professional prescribes
Diabetologia 59 , 14121421 (2016)
Retrieved 10 March 2013
This triple mechanism produces synergistic effects on appetite suppression, energy expenditure, and glucose metabolism that exceed single or dual agonists
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