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It is the natural endpoint of what pharmacotherapy can achieve, and the results represent a transformation that most people could never sustain through diet and exercise alone
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I believe there is still strong selection and immortal time bias present in this study, the early divergence in figure 2 is a concern
Trulicity is not approved for use by anyone younger than 10 years old with type 2 diabetes
Metformin remains a firstline drug for blood sugar regulation, with weight loss as a secondary benefit
Other perimenopause symptoms that can understandably leave you on edge: unpredictable menstrual cycles abdominal weight gain (aka meno belly) cognitive struggles (aka brain fog) hair loss achy joints loss of sex drive bladder issues (incontinence, for one) Many women report feeling unprepared for menopause and dont immediately connect their symptoms to their hormones
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