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Pentoxifylline, an immunomodulator and anti-inflammatory agent, has been specifically investigated for endometriosis-associated infertility and pain management

438 Functional MRI studies have reported augmented blood oxygen level-dependent (BOLD) responses in limbic and striatal structures in response to heat pain in PDPN patients

The most common adverse effects are gastrointestinal , occurring in 20-50% of patients and including nausea, vomiting, diarrhea, constipation, and abdominal pain

However, the timeline for recovery varies considerably between individuals

Glutathione is synthesized in the body from the amino acids L-cysteine, L-glutamic acid, and glycine

++, significant improvement in predefined outcome judged by gold-standard method