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Glutathione-S-transferase selective release of metformin from its sulfonamide prodrug

The medication belongs to a family of drugs called GLP-1 agonists, which were developed and initially approved to treat Type 2 diabetes

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Across agents, the available human pregnancy-exposure data remain sparse, exposure timing is heterogeneous, and existing studies are underpowered for rare outcomes

These side effects include: Itchiness, redness at the site of injection Dizziness or headaches Increased heart rate (mild tachycardia) Infections More serious complications are also possible, such as pancreatitis, intestinal or bowel blockages, and gastroparesis

Liver Fibrosis: Mechanisms of Immune-Mediated Liver Injury