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These data indicate that the effects described in this review are not unique to PGN, but are more likely common effects observed with regular ingestion of high concentrations of low molecular weight ( 50,000 Da .) sulfated polysaccharides

doi: 10.1038/s41392-022-00917-z 137 CuiYZhangYZhaoXShaoLLiuGSunCet al

Furthermore, the STEP-TEENS trial demonstrated semaglutides effectiveness in reducing BMI and cardiometabolic risks in obese adolescents, suggesting its potential for use in younger populations (40)

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Smoking addiction is another critical condition that exacerbates obesity-related health risks, significantly increasing the likelihood of developing or reinforcing cardiovascular disease, type 2 diabetes, and chronic obstructive pulmonary disease (120)