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IL received grant support from Merck, Mylan, Novo Nordisk, Pfizer and Sanofi, personal fees from AstraZeneca, Boehringer Ingelheim, Eli Lilly, Intarcia, Janssen, Mannkind, Novo Nordisk, Sanofi, TARGETPharma and Valeritas
Many patients do very well with standard once-weekly dosing
Dose calculations at 5,000 mcg/mL: 1mg dose = 0.2mL = 20 units on U-100 syringe 2mg dose = 0.4mL = 40 units 4mg dose = 0.8mL = 80 units 6mg dose = 1.2mL = 120 units 8mg dose = 1.6mL = 160 units 12mg dose = 2.4mL = 240 units This dilution makes higher doses more practical within a single syringe for mid-range protocols
The key financial metric to track is revenue per patient per year, which in a robust weight loss program typically ranges from $2,000 to $5,000
This study is supportive of further investigating the clinical application of GLP1 receptor agonist for HIE but also more widely for other neurological diseases
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