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Diabetes itself creates a hypercoagulable state
Homocysteine and oxidative stress
Expert Review of Endocrinology & Metabolism, 2025) The Fertility Paradox Worth Discussing With Your Provider For patients not actively trying to conceive, restored ovulation can be an unexpected and clinically significant side effect of treatment meaning contraception planning should be part of the conversation when starting GLP-1 therapy for PCOS, not an afterthought
Once-weekly treatment with EX-LAR (considering the potential beneficial effects of GLP-1R activation on cells and weight loss associated with many patients) is a promising potential strategy for diabetes prevention
High retail prices for GLP1 therapies, supply shortages and questions about longterm safety have constrained uptake for some patients
Continued research is required to clarify its broader scientific relevance
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