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Description

Inflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologies

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Endoplasmic reticulum stress triggers a cellular response known as the unfolded protein response (UPR), which aims to restore ER homeostasis

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doi: 10.1245/s10434-017-5982-4 19 HelyerLKVarnicMLeLWLeongWMcCreadyD

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Together, our results fill the knowledge gap by establishing SLC25A40 as a myeloid-relevant mtGSH transporter with a non-redundant role in cytokine production and a regulatory mode that is distinct from SLC25A39

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Weight loss also significantly improves insulin sensitivity, a crucial factor for women with PCOS

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