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To view or add a comment, sign in For nearly two decades, enzyme replacement therapy (#ERT) for #MPS-I has meant essentially one thing: a weekly, hours-long intravenous infusion that sustains patients but leaves two territories almost untouched the brain and the bone

This multi-target approach is believed to support broader metabolic effects than single-target agents

Measurement of oxidative stress markers was performed by measuring oxidative stress in vivo with simple and accurate tests, d-ROMs-derived compounds and BAP test

This makes it stronger and lets it turn on many different receptors at once, including MC1R, MC3R, MC4R, and MC5R

Miller et al., 2000)

Is there clinical evidence that this can help