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To treat them, you'll probably need shots of vitamin B12 at first, and then you may need to keep getting shots, or taking high doses of a supplement by mouth or nasally

These products differ in how they are made, how much vitamin B12 they contain, and how often they should be given

People with depression often also suffer from insomnia and other sleep disturbances

It is not approved for human or veterinary use, and no therapeutic claims are made

Chou MH, Lin MF

Cycle 8 weeks Weeks 14 300 mcg once daily Later weeks 500 mcg once daily during weeks 58 Review points Weeks 4 and 8 Evidence label Community standard Cycle 12 weeks Weeks 14 300 mcg once daily Later weeks 500 mcg once daily during weeks 512 Review points Weeks 4, 8, and 12 Evidence label Community standard Cycle 16 weeks Weeks 14 300 mcg once daily Later weeks 500 mcg once daily during weeks 516 Review points Every 4 weeks Evidence label Community standard No controlled human study has tested these subcutaneous schedules