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Starting at a low dose and gradually increasing over weeks helps minimize digestive side effects and gives your body time to adjust
They draw water into the bowel, softening stools and increasing frequency Bulk-forming laxatives (ispaghula husk, methylcellulose) work similarly to dietary fibre and are generally suitable for long-term use, but should be avoided if you have severe bloating or suspected impaction Stimulant laxatives (senna, bisacodyl) should be reserved for short-term use when other measures fail Rectal treatments (glycerol suppositories, small-volume enemas) can provide rapid relief for occasional constipation Establishing a regular toilet routine can be beneficial
Anaemia and metabolic factors : Diabetes-related complications including chronic kidney disease can cause anaemia, manifesting as breathlessness and fatigue
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Vitamin B12 deficiency can lead to depression and consistently low mood
Patients also can increase the dosing frequency of Rytary capsules from three times a day to five times daily, if more frequent dosing is necessary
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