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They performed genotyping of the A/G SNP (rs28674628) in the 3UTR of the IGF1R gene for 115 Ashkenazi Jewish BC patients, all carriers of the 185delAG BRCA1 mutation and found that all BRCA1 carriers harboring the G allele of the rs28674628 SNP were diagnosed with BC by age 45 years, whereas almost 50% of the wild type (A) allele homozygotes were BC free at that age
The test reveals predispositions in antioxidant pathway genes, which may help provide context for your baseline oxidative capacity
Wadzinski, J., Franks, R., Roane, D., and Bayard, M
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