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The data were fitted in GraphPad Prism (GraphPad Software, La Jolla, CA) using a heterologous one site-fit Ki competitive binding model

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Expired or degraded Wegovy may have reduced efficacy and should not be used

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3 It improves endothelial function and reduces oxidative stress

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Even when used at low dose, APAP causes the impairment of mitochondrial respiratory chain, decreasing ATP reservoir and promoting reactive oxygen species accumulation 3

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