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On Day 3 post-injury, GHK-AgNPs and GHK-Cu-AgNPs achieved the highest closure rates (32% and 31%, respectively) compared with GHK-Cu and the positive control (both 25%) and the negative control (22%)

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Bowers and DeGraffenried, 2015)

The main incretin hormones secreted by the epithelial cells of the gastrointestinal track are glucagon-like peptide-1 (GLP)-1 and glucose-dependent insulinotropic peptide, also known as Gastric Inhibitory Polypeptide (GIP), which stimulate the pancreatic cells ( and cells) and regulate insulin secretion with respect to blood glucose concentration (Drucker, 2006)