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Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
Beyond transient soreness, uncommon but noteworthy adverse events include nodules, infection, or allergic reactions
Antioxidant pathways induced by NRF2 include enzymes for the reduced GSH synthesis, utilization, and regeneration
One explanation for this finding is that Pelo stability is disrupted in the absence of Hbs1, and the destabilisation of its tertiary structure leads to the premature degradation of the protein in vivo
Kim et al., 2024
