Some of synthetic coloring additives cause severe tension to the consumer as general health for example tartazine E 102 and chocolate brown as synthetic coloring agents caused DNA liver and kidney damage as detected by comet assay [7]
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Harlia E, Rahmah KN, Nora L, Nababan JA, Hidayati YA, Marlina ET, et al
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Schneider F et al (2021): Pharmacokinetics of Deutetrabenazineand Tetrabenazine: DoseProportionality and Food Effect