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The incidence rate ratio (IRR) of subsequent cancer in patients with T2DM was 1.73, which was higher than that of individuals without DM, and it increased in both men and women

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Today, medical guidelines remain cautious, but they now recognize that GLP-1s might help some people with type 1 diabetes, especially those with insulin resistance or excess weight

Notably, both EAE and MS patients exhibited significant reductions in claudin-11, further implicating TJ dysregulation in disease pathology [142]

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