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Upjohn (now Pfizer) developed a topical formulation, and the FDA approved 2% minoxidil for hair loss in 1988, followed by 5% in 1991

Additionally, glutathione doesnt absorb well from the intestines

Protective effects of glutathione and lipoic acid against cadmium-induced oxidative stress in rat's kidney

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2 These agents are useful against dyskinesia, dystonia, and motor fluctuations, but they carry a higher risk of nonmotor side effects, such as sleepiness, postural hypotension, peripheral edema, and neuropsychiatric issues, compared with levodopa