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demonstrated that this ortholog (CHAC-1) is regulated by both the transcription factor ATF-4 and the mTORC1 pathway, linking it functionally to the reverse transsulfuration pathway
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One study showed that overexpression and hyperphosphorylation of tau induced ferroptosis in nerve cells (57)
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Mitochondrial thiols in the regulation of cell death pathways
This synergistic effect arises because a lowcalorie diet reduces fat intake, while it promotes lipolysis and energy expenditure, together achieving more efficient fat reduction and metabolic improvement
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