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A tannic-acid functionalized ZIF-8 carrier (TA-ZIF) was loaded with PTHrP-1 (TA-ZIF@P1) and combined with a boronic-acid modified gelatin hydrogel (GP) to form a GPTP hydrogel (GP@TA-ZIF@P1)
Higher doses were associated with greater weight loss within the initial 4 weeks of treatment [see Warnings and Precautions (5.5)]
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In most studies on IGF-1 Lr3 no adverse side effects were reported with use for 4-8 weeks (per the dosage limits in the above answer) followed by 4 weeks of non-use.
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