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Tirzepatide induces weight loss in patients with type 2 diabetes regardless of baseline BMI: a post hoc analysis of SURPASS-1 through -5 studies (abstract)
People should view a compounded product as a trade-off: lower cost or greater availability in exchange for less oversight and greater uncertainty
The recently published CAROLINA study, which compared the cardiovascular-safe DPP-4 inhibitor linagliptin [61] with the sulfonylurea glimepiride, showed that glimepiride does not increase the risk of hospitalization for heart failure [62]
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The metanalysis includes 5,323 patients (56-61 years) with T2D inadequately controlled (HbA 1c 7-10.5%), baseline BMI 23-45 kg/m 2 , mean diabetes duration of 9-12 years, and randomized to receive a GLP-1RA or GIP/GLP-1RA versus placebo in add on to basal insulin for at least 24 weeks (24-40 weeks)
Unlike triptans, NSAIDs do not target serotonin receptors or migraine-specific blood vessel pathways
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