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A still unsolved issue, connected with the role of carnitine in modulating gene expression (Figure 1) is the link between mitochondria and nucleus: acetylcarnitine produced in mitochondria would reach the nucleus providing acetyl units (Figure 2)

Nat Commun 16 , 6447 (2025)

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Theres a region in your brain called the VTAthe ventral tegmental area

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