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These findings position GLP-1RAs as a potential fourth pillar of kidney-protective therapy in diabetes, alongside renin-angiotensin system inhibitors (RASi), SGLT2i, and finerenone, and suggest a shift toward rapid initiation of combination therapies for maximum kidney protection
12 : e130e140
Nonetheless, mazdutide and tirzepatide carry warnings about medullary thyroid carcinoma and are contraindicated in patients with personal or family history of this rare cancer or multiple endocrine neoplasia syndrome type 2
N., Brownell, K
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There is an incredibly large leap from anecdotes and rat testing to human applications
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