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[1] The authors reported that methylquinolinium analogs with primary-amine substitutions displayed high permeability from passive and active transport across membranes, measured using two standard in-vitro models: the parallel artificial membrane permeability assay (PAMPA) and Caco-2 human intestinal cell monolayers
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This process leads to the breakdown of functional proteins within cells, causing DNA damage, and ultimately initiating apoptosis (Tuo et al., 2022)
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