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2 3 Following receptor activation, experimental investigations suggest that PT-141 may stimulate hypothalamic neurons and increase neuronal activity within regions of the central nervous system associated with behavioural regulation
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Exercise intolerance can even lead to Post-Exercise Malaise (PEM), a delayed and abnormal worsening of various symptoms and loss of energy following minimal physical or cognitive stressors or other triggers that would have been tolerated normally before disease onset (261, 262)
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