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This cardiovascular benefit is now part of the FDA-approved indication for Wegovy
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MT-1's mechanism requires concurrent UV stimulus to drive melanin synthesis
thus, it may induce hypoglycemia and it is contraindicated in patients with advanced liver insufficiency.66 In contrast, the pharmacodynamics of nateglinide is not altered in patients with CLD and is thus expected to be safer.67 Incretin-based therapies Incretin-based therapies comprise injectable glucagon-like peptide-1 (GLP-1) receptor agonists and oral inhibitors of dipeptidylpeptidase-4 (DPP-4)(gliptins)
doi: 10.1016/j.cell.2015.02.047 40 MahmoudianDehkordiSArnoldMNhoKAhmadSJiaWXieGet al
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