Apart from mitogenic, motogenic, and morphogenic properties, c-MET also protects against apoptosis by its interaction with PI3K/AKT (phosphatidylinositol 3-kinase/protein kinase-B) pathway
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The combined formulation provides a framework for studying interconnected pathways involved in tissue remodeling, cellular communication, and regenerative biochemistry relevant to mammalian models
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In addition, further in-depth molecular and cellular insight into the complex biology of FcRn will very likely inspire the development of innovative strategies and engineering of protein designs that can manipulate ligand binding and receptor transport properties