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In general, it is assumed that AT 2 receptors oppose the responses mediated by AT 1 receptors

Congestion still clears, but more gradually

Bottom line High vitamin B12 on a blood test is common and usually harmless when it results from supplements or B12 injections

Insider's takeaway The Institute of Medicine has not established a tolerable upper intake level of B12 because studies show no adverse health effects when taking excess levels of B12, either through food or supplements

Investigations focus on molecular mechanisms and assay readouts only