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The resulting cDNA was preamplified with 12 thermal cycles using the Fluidigm Preamp Master Mix and Delta Gene Assays according to manufacturers protocol

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DOI: 10.1021/jm500766w Future Oncol

To cope with the elevated oxidative stress they generate, cancer cells enhance their antioxidant capacity, largely through sustained activation of the transcription factor NRF2 often driven by mutations in its negative regulator KEAP1

Scientists have figured out how the new weight-loss drug, Retatrutide, works at a molecular level

(Reporting by Sneha S K in and Sriparna Roy in Bengaluru