GLP-1 medications like Ozempic, Wegovy, Zepbound, and Mounjaro have become household names, and the weight loss results can be remarkable
Studies have demonstrated its efficacy in improving glycemic control, with potential applications including obesity, nonalcoholic fatty liver disease (NAFLD), and heart failure with preserved ejection fraction (HFpEF).In the SURPASS-3 trial, once-weekly subcutaneous tirzepatide at 5 mg, 10, or 15 mg proved non-inferior and superior to semaglutide 3 mg dose in terms of decreasing glycated hemoglobin levels over 40 weeks
We wanted to ask whether separate neurons and separate brain circuits mediate the weight loss effects versus the nausea and the side effects of these drugs, said Alhadeff
PMID 11118871
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Ghasi S, Nwobodo E, Ofili JO