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In PTSD mice models, trauma exposure increased tyrosine hydroxylase expression (the rate-limiting enzyme in catecholamine biosynthesis), elevating stress hormones epinephrine and norepinephrine in serum and colon, which upregulated claudin-2 expression, confirming gut barrier dysfunction (Yadav et al., 2023)
This interaction can occur by itself, but occurs at a much faster rate with the assistance of a group of enzymes call the Glutathione-S-Transferases (GST)(figure1) (5)
Curcumin attenuates ethanol-induced hepatic steatosis through modulating Nrf2/FXR signaling in hepatocytes
Disuse-induced nitration was examined by using the 5-day tail-suspension model for hind-limb muscle inactivity
By focusing on the social determinants of health, global health systems and the systemic barriers faced by this community, we aim to foster a deeper understanding of disability as a critical aspect of diversity, equity and inclusion in global health
