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Diabetology International, 13 ,
Mechanistic studies reveal that neuronal ferroptosis susceptibility stems from three synergistic factors: high baseline iron retention in substantia nigra and hippocampal regions, GPX4 expression levels 40% lower than in glial cells, and preferential accumulation of polyunsaturated fatty acids in neuronal membranes (Sharma and Flora, 2021)
A.NguyenL.ColmanR
Source: Sikiric et al., Curr Pharm Des 2018
Most patients notice results within a few days
Bunner AE, et al
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