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A 2021 systematic review of 16 randomized controlled trials and 6,276 participants (Markun and colleagues, Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue, Nutrients, 2021) found that B12 supplementation does not reliably reduce fatigue in people who are not deficient
Available in 2 MG, 5 MG and 10 MG vials, supplied as lyophilized powder for reconstitution
Cyanocobalamin is the FDA-approved standard for treating deficiency and is praised for its stability
While generally considered safe under medical supervision, like any medication, it may cause some side effects
Repeating the blood test can help differentiate between a temporary spike (for example, after an injection) and a persistent elevation
Peripheral nerve blocks: Injected around a specific nerve or bundle (e.g digital block for a finger, dental blocks, brachial plexus block for arm surgery, intercostal blocks for rib pain, etc.)
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