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Roullet FI, Lai JKY, Foster JA (2013) In utero exposure to valproic acid and autism A current review of clinical and animal studies
This flexibility enabled regulators to tailor safety monitoring based on actual risk profiles observed during drug development, facilitating the approval of drugs like GLP-1R agonists for broader therapeutic use, including in non-diabetic populations with Cardiovascular-Kidney-Metabolic (CKM) Syndrome
This constant elevation can cause significant side effects including insulin resistance, carpal tunnel syndrome, fluid retention, and potential concerns about stimulating abnormal tissue growth
(2024) "Effect of Semaglutide on Cardiac Structure and Function in Patients With Obesity-Related Heart Failure" Journal of the American College of Cardiology, Epub 2024 Aug 30 6
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