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Glutathione has also emerged a key modulator of xenobiotic toxicity, most notably the persistent organic pollutants which are associated with many diseases of impaired metabolic activity, including diabetes, obesity, and cardiovascular disease

Biobehav Rev

System X(c) (-)/GSH/GPX4 axis: an important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy

288 the NRF2KEAP1 antioxidant response pathway, which reprograms redox metabolism and drives multidrug resistance

The study results also revealed a significant reduction in malondialdehyde, the livers cell damage marker

Unlike macroautophagy, the lysosomal membrane invaginates or protrudes to directly engulf cytoplasmic material during microautophagy (140)