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Long-Term Safety Considerations: While safety data from clinical trials spanning up to 24 weeks is reassuring, long-term safety data spanning years of continuous use remains limited
Adequate studies in humans have not been conducted
The same formulation principles pH optimization (5.0-6.5 for copper peptide stability), appropriate preservation, and penetration enhancement strategies apply whether formulating AHK-Cu alone, GHK-Cu alone, or a combination of both copper peptides in a single topical preparation
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They include pain or redness at the injection site, slight swelling or tenderness, mild diarrhea, and sometimes itching or a generalized feeling of body swelling
A study in the Journal of Clinical Pharmacology showed 1,000 mcg shots work well
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