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CagriSema submitted for FDA approval in December 2025 with expected approval in Q4 2026 or Q1 2027, meaning launch around mid-2027
This stress damages melanocytes directly, causes mitochondrial dysfunction, and triggers what scientists call the unfolded protein response (UPR) an internal alarm system inside cells
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It may be a poor fit if your dog has unexplained symptoms, is on complex medications, or is eating a tightly managed therapeutic diet without veterinary approval
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