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Jaiser and Winston, 2010) (Table 2)

TABLE 2 Differential diagnosis of diseases with clinical manifestations similar to neurological damage caused by N 2 O abuse

Benzyl alcohol toxicity in this population causes Gasping Syndrome, a potentially fatal condition characterized by metabolic acidosis, respiratory distress, and neurological deterioration

Starting with a lower dose and slowly increasing over several weeks helps most people manage these effects

Neither is approved for human consumption or therapeutic use in the UK

Other techniques measure barrier function in a broader sense, for instance bacterial translocation of lipopolysaccharide or epithelial cell damage with assays measuring fatty acid binding protein or citrulline