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Users of GLP-1s indicated for weight loss experienced a three percentage point improvement compared to the control group between 12 months and 18 months post GLP-1s initiation

The additional content of clinical features of specimens are showed in Supplementary Table 1

The evidence is promising but mostly preclinical, meaning much of it comes from animal and laboratory research rather than large human trials

It promotes the macrophage transition from M1 (pro-inflammatory) to M2 (anti-inflammatory)

doi: 10.1016/S2213-8587(17)30412-6 118 MarsicoFPaolilloSGargiuloPBruzzeseDDell'AversanaSEspositoIet al

However, mild effects such as temporary redness, tingling, or dryness may occur, especially after microneedling or injection procedures